Garcia slotted home into the lower left of the net after getting a pass from Christian Stuani and finishing the move with a right foot.
Garcia was on the pitch for 89 minutes against Real Betis. The striker scored in the seventh minute and took three shots.
The Periquitos now sit in 12th in the table with a record of eight wins, nine losses and seven draws.
Los Beticos are in eight place, and in striking distance of Real Sociedad in sixth with a record of 11 wins, 10 losses and three draws leaving them one behind after 24 games.
Espanyol had the ball for 43.0% of the match.
Los Blanquiazules had eight shots, four of which were accurate.
Real Betis had 57.0% of the possession during the match. Los Verdiblancos had eight shots, including one on target.
Javi Chica had three shots for Real Betis, more than any of his team-mates.
Damien Perquis was brought on to replace Paulao in the 85th minute when the latter went down with an injury.