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City are without captain Vincent Kompany, meaning a probable start for Joleon Lescott. Ryan Nelsen is set for his final QPR appearance.
January signings Moussa Sissoko, Mathieu Debuchy, Mapou Yanga-Mniwa and Yoan Gouffran could all be in the Newcastle squad.
Neither manager can call on any reinforcements, but Michael Laudrup is likely to recall Michel Vorm in place of Swansea's 'cup keeper' Gerhard Tremmel.
Glenn Whelan is free to play for Stoke after avoiding punishment for his FA Cup challenge on Manchester City's Javi Garcia.