Aguero, meanwhile, could only make the substitutes' bench after recovering from a hamstring injury.
Liverpool are unchanged from the side who beat West Ham 2-1 at Upton Park last weekend.
Brendan Rodgers's side have their title destiny in their own hands as they target a first top-flight crown since 1990, but City will present a significant obstacle as they sit four points adrift, but with two games in hand.
Liverpool: Mignolet, Johnson, Flanagan, Sakho, Skrtel, Gerrard, Henderson, Coutinho, Sterling, Suarez, Sturridge. Subs: Jones, Toure, Agger, Aspas, Moses, Allen, Lucas.
Manchester City: Hart, Zabaleta, Kompany, Demichelis, Clichy, Toure, Fernandinho, Navas, Nasri, Silva, Dzeko. Subs: Pantilimon, Lescott, Kolarov, Garcia, Milner, Negredo, Aguero.
- Sports & Recreation
- Manuel Pellegrini