"Please support us in our common fight with Michael," she said in a statement.
"It is important to me that you leave the doctors and the hospital alone so that they can work in peace.
"Please have faith in their statements and leave the hospital. Please can you also leave our family in peace."
Mrs Schumacher's statement came after a statement from the hospital on Monday in which they confirmed that the legendary driver is stable, but remains in a life-threatening, critical condition.
The hospital statement added that neither the doctors nor the hospital would issue any further statements for the time being, but French authorities investigating the incident have said they will hold a press conference in Albertville on Wednesday morning to discuss their findings so far.
The retired seven-times Formula One world champion slammed his head on a rock while skiing off-piste on December 27.
Schumacher has been in an induced coma since then and has undergone two operations in Grenoble.
The medical team and the German's management repeated on Monday their call to respect his privacy and said they would not send any more statements nor hold any news conference until further notice.
Last week his agent Sabine Kehm urged journalists to stay away from Schumacher after security guards said they intercepted a reporter disguised as a priest who was trying to get into his room.
"The patient's privacy requires that we do not disclose any details about his treatment and that's why we do not plan any news conference nor written statements for now," said the medical team and Schumacher's management.
"We ask you again, insistently, to ... stick to the information provided by the medical team in charge or his management because they are the only valid ones."
While Schumacher is battling for his life after suffering severe internal bleeding on the skull, French authorities are investigating the accident that took place in the Alps resort of Meribel.
The Annecy prosecutor on Monday said he will hold a news conference on Wednesday.
Schumacher, who turned 45 on Friday, is the most successful Formula One driver of all time with 91 race victories.
He left the sport last year after a disappointing three-year comeback with Mercedes following an earlier retirement from Ferrari at the end of 2006.