Tottenham stretched their unbeaten run to five matches in all competitions on Thursday when they beat Anzhi Makhachkala 4-1 in the Europa League.
Memories of the 6-0 drubbing at Manchester City have more or less faded, but Tottenham still have a lot of work to do if they are to gain Champions League qualification.
They will face one of their trickiest hurdles this weekend when Suarez comes to White Hart Lane having scored 15 goals in his last 11 matches.
With Daniel Sturridge and Steven Gerrard both out through injury, the onus will fall on Suarez to provide the goals for the Reds again this weekend, and Villas-Boas hopes he can keep the former Ajax striker quiet.
"He's a player going through a wonderful individual moment," the Tottenham manager said.
"He's full of the confidence. We have to be aware of his strengths.
"He's a player that individually can solve the game.
"So we have to be aware not only of the people that feed him but the actual individual moments of brilliance that we saw this season, that have been so decisive for Liverpool.
"He's a key player for them and very difficult to stop."
Tottenham's own first-choice striker Roberto Soldado also goes in to the match full of confidence after scoring a hat-trick in midweek.
The Spaniard tucked away a tidy header and then produced a top-class finish before scoring his fourth penalty for Spurs.
Soldado oozed confidence after scoring his first and he swaggered his way through the rest of the match, demanding the ball and bouncing off defenders just like he did on a regular basis for Valencia.
Confidence is coursing through the veins of most of the Tottenham players at the moment following their recent unbeaten run.
Villas-Boas' position came under scrutiny a few weeks ago, but now he is glad that things are on the up.
"We have had a good recovery and a good response from the team from that setback," Villas-Boas said.
"If we manage to get a win against Liverpool we're completely back on track with the top teams.
"It's a big, big game for us - we won't be that far off, even if we don't win that game."