Former Bayern Munich, Blackburn Rovers and Manchester City striker Santa Cruz put the South Americans further ahead when he tapped in from close range in the 68th minute, the 32-year-old's 29th international goal.
Eric-Maxim Choupo-Moting pulled one back for the Indomitable Lions with 15 minutes left and Mohamadou Idrissou wasted a chance to equalise when his 87th-minute penalty was saved by Paraguay's substitute goalkeeper Victor Centurion.
There was a minor pitch invasion at the end as fans ran on to the field to take photographs with the players.
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- Oscar Romero
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- Blackburn Rovers
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