The Swiss keeper suffered a facial injury during Saturday's 3-1 home defeat to Sheffield Wednesday following a collision with Owls defender Reda Johnson and received lengthy treatment on the pitch.
Jakupovic, who had inexplicably dropped Miguel Llera's corner over the goalline moments earlier, has been given the all-clear after medical tests and is likely to start at Brisbane Road as his replacement on Saturday Mark Oxley is cup-tied, having featured for Burton earlier in the competition.
Manager Steve Bruce has no other new injury or suspension worries, while striker Sone Aluko (calf) and midfielder Robert Koren (heel) are expected to retain their places after returning from injury lay-offs against Sheffield Wednesday.
Strikers Nick Proschwitz and Jay Simpson, plus defenders Paul McShane, Liam Rosenior and Alex Bruce are all pushing for recalls.
- Sports & Recreation
- Reda Johnson
- Sheffield Wednesday
- Miguel Llera