England have never played Lithuania before, but San Marino have been regular opponents - in 1993 they famously scored after just 8.3 seconds against England after an attempted back-pass by Stuart Pearce.
England went on to win 7-1 - and have scored at least five goals in the four games they have played. Estonia should also pose little problem, with England playing them twice in 2007 and winning 3-0 home and away. Switzerland will be England's biggest challenge, having secured a 2-2 draw at Wembley in qualifying for Euro 2012.
Scotland and the Republic have tough campaigns ahead after being drawn together in Group D along with Germany, Poland and Georgia, as well as UEFA's newest member Gibraltar, who were drawn to Group C with Spain but were switched to D for political reasons.
Wales have a shot at a play-off place or better in Group B, where they will face Bosnia-Herzegovina, Belgium, Israel, Cyprus and Andorra.
It is a similar story for Northern Ireland, who were drawn in Group F with Greece, Hungary, Romania, Finland and the Faroe Islands in a competitive-looking group.
Spain will start their campaign for a third successive European title in a group with Ukraine, Slovakia, Belarus, Macedonia and Luxembourg.
Italy, runners-up to Spain in 2012, will meet Croatia, Norway, Bulgaria, Azerbaijan and Malta in their section.
The top two in each group will qualify for the 24-team final tournament along with hosts France. The best third-placed team will also qualify, with the eight other third-placed sides playing off for the remaining four spots.
Groups in full:
Group A: Netherlands, Czech Republic, Turkey, Latvia, Iceland, Kazakhstan
Group B: Bosnia-Herzegovina, Belgium, Israel, Wales, Andorra, Cyprus
Group C: Spain, Ukraine, Slovakia, Belarus, Macedonia, Luxembourg,
Group D: Germany, Republic of Ireland, Poland, Scotland, Georgia, Gibraltar
Group E: England, Switzerland, Slovenia, Estonia, Lithuania, San Marino
Group F: Greece, Hungary, Romania, Finland, Northern Ireland, Faroe Islands
Group G: Russia, Sweden, Austria, Montenegro, Moldova, Lichtenstein
Group H: Italy, Croatia, Norway, Bulgaria, Azerbaijan, Malta
Group I: Portugal, Denmark, Serbia Armenia, Albania, (France*)
*France qualify automatically as hosts so any fixtures they are involved in in Group I will be played as friendlies with no qualification points at stake.