Broncos 37, Texans 13
Peyton Manning passed for 400 yards and set an NFL single-season mark for touchdown passes as the Denver Broncos clinched the AFC West crown with a crushing road win over the Houston Texans.
With his 25-yard touchdown pass to tight end Julius Thomas at the 4:28 mark of the fourth quarter, Manning recorded his 51st scoring pass this season and eclipsed the mark set by New England Patriots quarterback Tom Brady in 2007.
Manning will enter the season finale 266 yards shy of Drew Brees' single-season record of 5,476 passing yards set in 2011 with New Orleans.
Denver (12-3) sent the Texans (2-13) to their 13th consecutive loss.
Bengals 42, Vikings 14
The Cincinnati Bengals topped the 40-point mark for a fourth consecutive home game and earned their third consecutive postseason berth with an emphatic win against the Minnesota Vikings (4-10-1).
Cincinnati improved to 7-0 at home this season as quarterback Andy Dalton finished 27 of 38 for 366 yards.
Panthers 17, Saints 13
Cam Newton threw a 14-yard touchdown pass to Domenik Hixon with 23 seconds remaining to lift the Carolina Panthers to victory against the New Orleans Saints and clinch a playoff berth.
The outcome broke a tie atop the NFC South, with the Panthers capable of clinching the division with another victory.
Carolina (11-4), in the playoffs for the first time since 2008, can grab the first-round bye as the No. 2 seed in the NFC and secure at least one home game by winning its finale at Atlanta.
Colts 23, Chiefs 7
Donald Brown scored touchdowns as a rusher and receiver and the Indianapolis defense forced four turnovers by the normally sure-handed Kansas City Chiefs in bone-chilling cold weather.
After falling behind on a quick Kansas City touchdown, Indianapolis ran off 23 unanswered points.
The Colts earned their 10th victory of the season and will host a first-round game in the AFC playoffs in two weeks.
Kansas City's defeat and Denver's victory over Houston eliminated any chance the 11-4 Chiefs had of winning the AFC West and locked them into the fifth seed in the AFC.
Cowboys 24, Redskins 23
Quarterback Tony Romo rallied the desperate Dallas Cowboys from a nine-point deficit with less than seven minutes left to edge the Washington Redskins and stay alive in the NFC East race.
After running back DeMarco Murray lost nine yards on third-and-goal from the Washington 1-yard line, Romo had all the time in the world to find him for the game-winning 10-yard touchdown pass with 1:08 left.
The Cowboys (8-7) can win the division by beating the Philadelphia Eagles at home next Sunday. The Redskins sank to 3-12 with their seventh straight defeat, the second in a row by a point.
Bills 19, Dolphins 0
The Buffalo Bills dealt a devastating blow to Miami's postseason hopes as they kept the Dolphins scoreless.
The Bills improved to 6-9, while the Dolphins, who had won three straight, dropped to 8-7 and limp home to face the New York Jets with quarterback Ryan Tannehill nursing a knee injury.
Jets 24, Browns 13
Quarterback Geno Smith threw a pair of touchdown passes to wide receiver David Nelson and rushed 17 yards for a third score as the New York Jets stormed back from a 10-point deficit to beat the Cleveland Browns in front of a sparse home crowd.
Rams 23, Buccaneers 13
Tampa Bay Buccaneers rookie quarterback Mike Glennon was sacked seven times and lost a key fumble as the St. Louis Rams overcame a handful of mistakes offensively to win at home.
Titans 20, Jaguars 16
Playing for nothing but pride at this point in the season, the Tennessee Titans wrapped up their road schedule with a win over the Jacksonville Jaguars.
Jaguars quarterback Chad Henne was intercepted by safety George Wilson on Jacksonville's potentially game-winning drive in the final minutes.