The Arsenal manager made the shocking claim when discussing the nature of injuries in his weekly press conference ahead of Sunday's game against Everton.
Wenger, who revolutionised the English game when importing new fitness and preparatory methods following his arrival at Arsenal in 1996, says some players are leaving themselves open to problems if they use products to reverse the process of balding.
And according to the Gunners boss, vanity could lead to injury.
Perhaps this explains Sir Bobby Charlton's longevity, as the Manchester United legend always displayed his balding pate with pride...
"Some (absences) are down to the medication that they take that you don’t even know about," said Wenger.
"Then you realise afterwards they took this medication, but that’s not prudent. The liver doesn’t work as well, toxins don’t leave the body as quickly as they should and they get tired.
"If you lose your hair, and if you’ve taken something to make your hair grow, it might not be good, especially for the rest of your body."
In March 2011, it was Wenger who revealed that his former defender Kolo Toure had failed a drugs test at Manchester City after taking a diet tablet belonging to his wife.
- Sports & Recreation
- Arsene Wenger