"Mattia Destro underwent surgery on his left knee at Villa Margherita today," the Serie A club said on their website (asroma.it).
"The operation...lasted 20 minutes and was a complete success. The recovery period is expected to be approximately eight weeks."
The 22-year-old Destro, who has scored four goals in 16 appearance this season, hurt his knee and his right ankle during the 2-1 defeat of Inter in the first leg of an Italian Cup semi-final on Wednesday.
Roma, who are seventh in Serie A on 33 points, take on Bologna on Sunday (1130 GMT).
