Rooney, who starred on the anchor leg in Team GB’s fourth-placed effort in the 4x400m relay at the London Olympics, finished ahead of Poland’s Marcin Marciniszyn and Duane Solomon of the USA.
In the women’s 200m, London Olympic champion Felix won convincingly in 22.35 with compatriot Charonda Williams and Aleen Bailey of Jamaica also dipping under 23 seconds.
Bailey, meanwhile, won the men’s 100m in a time of 10.02 with former world champion Kim Collins of St Kitts and Nevis in second and fellow American Darvis Patton in joint-fourth place with Jamaica’s 4x100m relay Olympic champion Michael Frater.
Jamaica’s Rosemarie Whyte exhibited fine end of season form to take the women’s 400m in 50.08 from Denisa Rosloova of the Czech Republic, with Britain’s Marilyn Okoro in third in 52.65.
Veteran sprinter Aleen Bailey of Jamaica (11.32) took a surprise third in the women’s 100m, which was won by Olympic triple medallist Carmelita Jeter in 11.07.
In the men’s 110m hurdles, London Olympic silver medallist Jason Richardson of the USA was victorious in a time of 13.07 from compatriot David Oliver, who was second in 13.22.
Shara Proctor produced another fine display for Britain in the women’s long jump, winning with a 6.79m effort with Chelsea Hayes and Funmi Jimoh of the USA unable to match her.
Lawrence Okoye of Britain also won his event, the discus throw, with a best effort of 67.25 as Eric Cadee of the Netherlands his only real challenger in second.