Yoan Gouffran scored his eighth league goal this season to put the visiting Bordeaux ahead in the 57th minute.
Henri Saivet powered home a splendid half-volley to double the lead nine minutes later as Bordeaux clinched their first win after five consecutive league draws.
Substitute Gaetan Charbonnier was twice on target in 12 minutes late on to earn champions Montpellier a deserved 2-0 victory over Lorient, who fell to sixth on 31 points as Montpellier climbed to ninth on 29.
Nolan Roux scored the fastest goal of the season after 21 seconds for 2011 champions Lille, who blew the lead twice to draw 2-2 at basement-side Nancy.
Nancy captain Andre Luiz left the pitch in tears in stoppage time after playing his last game in an eight-year spell before he heads back to his homeland Brazil.