The British driver secured his seventh pole position of the season on Saturday, leading team-mate Jenson Button to an all-McLaren front row.
Although Hamilton acknowledged they were in the best possible situation to win on Sunday, he is aware that the race will be very difficult if it rains.
"I think the weather is going to be tricky tomorrow so will definitely make it more of a lottery," said Hamilton.
"We have put ourselves in a really good position and we will do best job we can as a team. It's the best we have been for quite some time, so we will do everything we can to get a top result."
Hamilton, in his last race with McLaren before moving to Mercedes, was thankful to his team for its performance in the latter part of the season.
"It has been a good weekend so far. I am grateful to be able to put the car on the front row and have my last one-two in qualifying with Jenson in the same team," said Hamilton, who won the United States Grand Prix last weekend.
"A fantastic job by the team. I'm so grateful for the all the opportunities they have given me and I hope to turn it into a positive tomorrow."
Hamilton suggested his team had not taken the gamble of going for a wet-weather set-up despite the chance of rain for Sunday.
"We have just set the car up to attack for qualifying," he said. "We don't know what the hell is going to happen tomorrow. We have to make sure we get our tyre temperatures right, and try and steer clear of any big puddles."