Having beaten Norwich on Boxing Day, hopes were high for a mini revival but they were dashed in brutal fashion as Ahmed Elmohamady, Robert Koren (2), George Boyd, Tom Huddlestone and Matty Fryatt got on the scoresheet in a rampant second-half display from the Tigers.
"I've asked myself what happened and I've asked the players. I didn't see this coming," Meulensteen said.
"I've been saying to all the media and all the press that the lads have been fantastic for me, that I can't fault the performances they've put in, that we haven't got the results we deserved but this is something completely different.
"Losing is hard to take but losing in such a manner is hard for any professional player."