Tuesday night's 1-0 defeat to Huddersfield was compounded by the loss central pair Dean Marney and Chris McCann with respective calf and hamstring problems and the duo are very doubtful for the trip to the Valley.
They would join winger Ross Wallace (knee) and defenders Michael Duff (calf) and Ben Mee (knee) on the sidelines but Dyche believes such situations provide opportunities for the likes of Marvin Bartley, who replaced McCann in midweek.
"It's touch and go with him (Marney) and Chris McCann, on top of the list that includes Duffo, Ben and Ross," he told the Clarets' official website. "I don't think they will be quite there for Saturday. Might be, but unlikely.
"They are important players but it gives others an opportunity to stand up and play and play well.
"Marvin Bartley came on the other night and was chomping at the bit and I was really pleased with his 25 minutes.
"People like that are coming to the fore and saying `Right, I'll have a go. I'm ready'. Let's see if they are."