A 2-2 draw at home to Liverpool was secured thanks to Sergio Aguero's angled strike 12 minutes from time after Daniel Sturridge, against his former club, and Steven Gerrard had turned things around after Edin Dzeko's opener.
However, they have dropped further behind leaders Manchester United and the gap is now nine points but Mancini said that was far from insurmountable.
"Absolutely not," was the Italian's response when asked whether the championship was over.
"Two years ago Chelsea were nine points behind and when they went to play at Old Trafford two games from the end (of the season) they were only two points behind.
"Two games and the championship is reopened. I don't think this is finished but probably now we have to win all the games but if not then 11 or 12 games.
"But in football this can happen sometimes.
"Last year we recovered eight points in six games so I don't know why it can't happen this year.
"We have 15 games and they (United) have to play in FA Cup and the Champions League so the season is long - three months - and we are confident.
"It is enough to recover three or four points in three games. For us it is important to play the derby (at Old Trafford on April 6) two or three points behind and we have time to recover these points."