The Europa League offers last season's Champions League winners an opportunity for a semblance of redemption in Europe after their humiliating exit from the top tier competition at the group stages.
Speaking ahead of Thursday night's last 16 first leg encounter with Steaua Bucharest, Luiz said: "This is a great opportunity to win another European title. Last season it was in the Champions League, everybody was happy.
"I have the hunger again and I think Chelsea have the hunger again to win titles.
"This is one big club. This is the way you need to think to play for a big club.
"It's an opportunity to win one more game, the first leg and we're looking for the title of the Europa League."
With Manchester United out of the Champions League, Arsenal's European campaign likely to be completed next week and Newcastle and Tottenham in challenging last 16 ties, Chelsea could again fly the flag in Europe this term.
Brazil international Luiz added: "It's important to show the Premier League is the best league in the world. Chelsea and other teams have the opportunity to show that.
"Last season we did a great job. This season we have another opportunity, in another competition, but it's still here."