Dimitar Berbatov's eighth-minute strike looked enough for the Whites to secure victory on a wet and blustery afternoon at Craven Cottage.
However, Rickie Lambert's penalty five minutes from time earned Southampton a 1-1 draw, meaning Fulham have won just one match in 11 attempts.
"I am like a thunderstorm, I am very angry," Jol said. "Sometimes with myself and sometimes you can do something about it.
"You want to change things and sometimes the players are not there to change things.
"I was very happy at half-time to be able to bring Bryan Ruiz on but it was not enough. He will be fit to start against Swansea.
"Against Liverpool, I was angry because we didn't have the weapons to play with and that's even more frustrating.
"I thought if we played in the way we could play, we could make a difficult for them.
"We could have scored again as we had a couple of chances, but it is not enough. You will never hear me say it was enough to earn three points because it wasn't."