Full-backs Bruno (Achilles), Inigo Calderon (knee) and Marcos Painter (calf) are all expected to miss out at Ewood Park, so centre-half Adam El-Abd looks set to deputise at right-back.
Gary Dicker (knee) and Andrea Orlandi (rib) are also likely to sit out again.
Fellow midfielder Liam Bridcutt was withdrawn during the second half of the 2-2 draw with Millwall on Tuesday night but manager Gus Poyet confirmed that was only as a precaution.
Winger Kazenga LuaLua has scored two goals in three substitute appearances and is pushing to make his first start since October.
Will Hoskins could also return to the starting line-up after dropping to the bench in midweek.