The 20-year-old sprinter, who won the Olympic omnium silver medal at London 2012, recorded his first professional victory on the road in a bunch gallop on Thursday and followed it up with success at the end of the 154km stage from Sabran.
He beat Lotto-Belisol’s Frederique Robert and Samuel Dumoulin (AG2R-La Mondiale) to the line.
Coquard's team-mate Jerome Cousin retains the overall lead going into the final day which sees a time trial and a short road stage.
Lieuwe Westra (Vacansoleil-DCM), Pierrick Fedrigo, Jeremy Roy and Arthur Vichot (FDJ), Ricardo Garcia Ambroa (Euskaltel), Georg Preidler (Argos-Shimano), Evaldas Siskevicius (Sojasun), Arnaud Gerard (Bretagne-Seche Environnement) and Julien Antomarchi (La Pomme Marseille) launched an early attack but were caught by a vigilant peloton.
However Antomarchi's team-mate Thomas Rostollan instigated another break and was joined by Axel Domont (AG2R La Mondiale) with the duo holding a lead of 5:50 with 41km remaining.
But they were reeled in 3km from the finish to set up a bunch sprint where Europcar took their fourth consecutive stage victory in the early-season five-day race held annually in Southern France.