Far from seeing the five one-day internationals as an also-ran element of this Ashes summer, the Australia captain is giving them top billing.
The series will get under way at Headingley on Friday - weather permitting.
The Ashes urn is in English keeping again, after a 3-0 home victory in Tests. But Clarke can cite an International Cricket Council table which sharply contrasts Australia's standing between the two formats.
"I think we're ranked second in one-day cricket...and in Test matches (fifth)...so I think there's a big difference," Clarke said.
Even so, after a 4-0 ODI defeat in this country last summer, Clarke knows a team that features many names who are unfamiliar to the English public will have a significant task on their hands.
"We've got a lot of young players coming through our one-day system...but in both forms of the game, we haven't been as consistent as we would like," he said.
"I think in patches we've played really well, and generally at home in our conditions pretty well.
"But we need to perform when we're away from home, and our most recent trips to the UK have not been successful. Let's hope we can turn that around."
An ODI series victory would perhaps ease any perceived pressure on Clarke's captaincy before they have to face England's Test tourists at the end of November.
But he does not acknowledge that as a relevant issue.
"When you're captain, you're accountable - especially when you're not performing well and your team is losing," Clarke said.
"I understand that. But me wanting to win this series has nothing to do with my captaincy.
"It's about this team, where we're at and trying to move forward and improve in the one-day format and get back to being number one in the world.
"That's why it's important we win this series."