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Carlo Ancelotti has taken a 21-man squad to Kiev for this match. Forward Jeremy Menez (thigh) is the most notable absentee, while midfielder Thiago Motta returns from a series of niggles. Zlatan Ibrahimovic returns from international suspension.
Porto have already qualified and as such may choose to rest first-team stars like Joao Moutinho and James Rodriguez. Dinamo have had some positive injury news as Arijan Ademi, Alen Halilovic, Mateo Kovacic and Domagoj Vida have all been passed fit.
Theo Walcott will miss the clash against Montpellier after hurting his shoulder in the 5-2 win over Tottenham at the weekend. Gervinho returns from an ankle injury that has kept him out for a month, so he will fill in for his fellow wide forward.
Schalke’s Dutch attacking midfielder Ibrahim Afellay missed training after pulling a thigh muscle on international duty, and he is expected to miss the match. If Arsenal and Schalke both win their games on matchday five, both sides will qualify for the next stage.
Milan have left experienced but injured midfielder Massimo Ambrosini behind, with youngster Bryan Cristante taken in his place although unlikely to feature. If Milan win and Zenit do not beat Malaga, the Italian side will qualify for the last 16.
The Russian side have a number of fitness problems with Italy international Domenico Criscito and Aleksandar Lukovic both missing. Malaga have already qualified for the last 16, but one point from either of their two remaining games will see them win the group.
Dortmund captain Sebastian Kehl looks set to feature against Ajax after missing a fortnight of action with a knee strain. If Dortmund avoid defeat against Ajax, their place in the last 16 will be secured.
Mario Balotelli is struggling to be fit for Manchester City in time for the crucial group stage encounter at home to Real Madrid. Real Madrid are without Argentina striker Gonzalo Higuain after he injured his thigh earlier this month, though Karim Benzema is fully fit. Manchester City will be eliminated from the Champions League if they do not win this match.