Mike Jones, who comes from Tarleton, Lancashire, was attacked in Manhattan in the early hours of Sunday morning.
Jones, who coached the New York Red Bulls juniors, was declared dead on arrival at Bellevue Hospital, New York.
The coach had been found with a severed ear and stab wounds to his head and neck, according to a NYPD spokesman.
"He was a tremendous individual, a fantastic coach who loved soccer and a terrific friend for many of us," the club said in a statement.
"This is truly a sad day for our soccer community and we will do our utmost to help authorities in their investigation of this case.
"Our thoughts and prayers are with Michael's family at this time."
Officers answering an emergency call found Jones on the street near 25 West 14th Street at about 04:30 local time.
The NYPD spokesman confirmed a "homicide investigation" was now under way.
Mr Jones had been a coach with the Youth Training Programme of the New York Red Bulls for the past five years.
He had moved to the US on a college scholarship and had been living in Westchester, New York.
Current players of the MLS side include former English Premier League stars Thierry Henry, formerly of Arsenal, and Tim Cahill, who played for Everton.