Fresh from his London 2012 adventure, where Selby lost at the quarter-final stage to eventual flyweight gold medal winner Robeisy Ramirez from Cuba, the Welshman has won all five of his contests in his debut season in the competition and is the highest-ranked boxer in the whole of the WSB.
And the 24-year-old will be looking to make it six wins from six after being named in the Lionhearts' five-strong team to compete in the home leg of the quarter-final against Mexico that will take place at York Hall in London on Friday March 22 – with the second leg taking place in Mexico a week later.
"The World Series of Boxing has been really good for me and I am enjoying the competition," said Selby, who will fight Aaron Alameda Lopez.
"For a boxer like me, who throws a lot of punches, competing over five rounds instead of three has been great.
"The extra rounds mean you have an opportunity to really settle into the bout and show your full range of skills.
"It does test your fitness, but that has not been a problem and I have lasted the pace well on every occasion. "My next opponent will be tough – like all Mexicans. But if I maintain my good form and continue to box and move then I am hopeful that I can come away with a victory and extend my unbeaten run."
Selby's fellow Welshman Fred Evans misses out after the Olympic welterweight silver medallist was stopped in the last contest against Ukraine.
Selby will be joined by Ireland 's Olympic silver medallist, John Joe Nevin, and his countryman, Joe Ward, who is currently ranked third in WSB’s light-heavyweight category.
Making up the Lionhearts team are Joe Joyce from London, who has won four from five and sits third in the heavyweight rankings, and Scotland's Aston Brown who will be making his first home appearance of the season at middleweight instead of Evans.