CJ Ross scored the contest 114-114 despite the general consensus being that Mayweather had dominated the fight.
Ross, who also drew criticism for awarding Timothy Bradley victory over Manny Pacquiao in June 2012, defended her scorecard of the Mayweather fight on Sunday but the criticism has clearly had an effect and the 64-year-old may now have judged her last fight.
Ross has been attacked in columns and blogs around the sports world and has even had a parody Twitter account set up in her name.
"To her credit, she does not want to take away from the story, being what a dominant performance by Floyd Mayweather," explained Keith Kizer, the executive director of the Nevada commission who appointed her.
"So, she has asked us if she can take some time off, [and] we've agreed. It shows the type of person she is"
Ross took the decisions after having a meeting with Billy Brady, the chairman of the Nevada Athletic Commission, to discuss her scorecard.
"Bill was very understanding and supportive. He agreed that that was a great avenue to take," explained Kizer.
Ross is a veteran of the sport and has been judging fights in Las Vegas for the last 22 years.
On Sunday, she explained her scorecard to the Las Vegas Review-Journal by saying: “When you score 12 rounds of boxing, you’re scoring 12 separate fights.
"From where I sat, there were a lot of close rounds and a lot of exchanges Canelo was able to win. Canelo was able to land his punches effectively from the inside and control the rounds I gave him.
“I have no problems with my scoring the fight the way I did.”