Ellsbury is out with a non-displaced compressed fracture of his right foot, Red Sox manager John Farrell said on Sunday, according to the team website.
Farrell said the Red Sox hope Ellsbury can return by the end of the regular season, which would allow him to participate in the playoffs.
Ellsbury, 29, was injured on Aug 28, when he fouled a ball off his foot.
He is batting .299 with 31 doubles and 52 steals in 56 attempts.
Buchholz has not pitched in a major-league game since June 8 because of a shoulder injury. He is scheduled to start Tuesday's game against Tampa Bay, the Boston Herald reported.
Buchholz was outstanding before the injury. He opened the season 9-0 with a 1.71 earned run average.
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Toronto Blue Jays outfielder Melky Cabrera had a benign tumor removed from his lower back, according to the team's website.
The tumor was near Cabrera's spinal cord, which was apparently putting enough pressure on his spine that it could be the reason for his leg injuries this season.
Cabrera, 29, was already ruled out for the rest of the season because of the injuries. He is expected to be ready by spring training.
He will enter the final year of a two-year, $16 million contract.
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New York Yankees shortstop Derek Jeter was left out of the lineup on Sunday after receiving a CT scan on his troublesome left ankle, which caused him to leave Saturday's game.
The results came back negative, but the team said Jeter is out indefinitely due to ankle soreness.
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San Francisco Giants catcher Buster Posey is in the lineup against the Arizona Diamondbacks after missing four straight games with a fracture at the tip of his right ring finger.
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New York Mets ace Matt Harvey will have Dr. James Andrews exam his sore right elbow to see if he needs reconstructive surgery.
Mets manager Terry Collins said Harvey will be examined this week, but no date was set. Harvey is on the 15-day disabled list with a partial tear of the ulnar collateral ligament.
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Pittsburgh Pirates pitcher Charlie Morton left his start on Sunday in the second inning with what the team called left foot discomfort.
Morton allowed five earned runs on six hits and two walks before exiting. He had a 1.74 ERA over his last six starts before Sunday.