Frenchwoman Marchand-Arvier, who was 10th in the first run on Wednesday, clocked a time of 1:51.45 to lead the way from Liechtensteiner Weirather.
German Maria Hofl-Riesch was third ahead of Slovenia's Ilka Stuhec.
American Lindsey Vonn, who already has four race wins to her name this season - a treble at Lake Louise and the super-G at Saint Moritz - was dead last in 48th, seven seconds off the pace, after an uncharacteristic error at Meadows.
1 MARCHAND-ARVIER Marie FRA 1:51.45
2 WEIRATHER Tina LIE 1:51.46
3 HOEFL-RIESCH Maria GER 1:51.62
4 STUHEC Ilka SLO 1:51.78
4 STERZ Regina AUT 1:51.78
6 FANCHINI Elena ITA 1:51.86
7 MAZE Tina SLO 1:51.88
8 RUIZ CASTILLO Carolina SPA 1:51.91
9 MERIGHETTI Daniela ITA 1:51.97
10 FENNINGER Anna AUT 1:52.26