Wales and England face on in a Six Nations decider on Saturday with England gunning for the Grand Slam, while the Welsh know an eight point win will see them defend their title.
It's set to be one of the best matches between the two for years - so to help get you in the mood, we're taking a look back at the best England v Wales sporting encounters of all time.
Rugby: Wales 32-31 England in 1999
Scott Quinnell celebrates after the last-minute try
Wales suffered the ignominy of having to host England in London, at Wembley, as the Millennium Stadium was not yet complete. And it looked like becoming a doubly sour day as the 'visitors' went deep into injury time leading by six points on their way to a Grand Slam.
Welsh centre Scott Gibbs had other ideas, however, breaking the line thanks to a stunning pop-up pass, evading four tackles and scoring more or less under the posts. Neil Jenkins converted, England lost their Grand Slam, and Scotland were crowned Five Nations champions for the final time.
Football: Wrexham 2-1 Arsenal, FA Cup in 1992
Wrexham were the bottom club in the Football League and given no chance whatsoever as they turned up to play George Graham's Arsenal, the reigning top-flight champions who were sitting second in the First Division.
But the fourth-tier side came from 1-0 down with eight minutes left to beat the Gunners 2-1 and record one of the great FA Cup giant-killings of all time.
Football: England 5-1 Wales in 1966
It was bad enough for Welshmen that their neighbours had won the World Cup just a few months beforehand, but when England destroyed their side at Wembley in November 1966 it rubbed further salt into the wound.
Football: England 1-1 Wales in 1973
Just seven years after that mauling at Wembley, John Toshack's goal at the same venue helped Wales to a 1-1 draw in their World Cup qualifier that felt like a win and left England needing a victory against Poland to make it to football's biggest tournament. England, famously, failed in their task, leaving the 1966 World Cup winners and 1970 semi-finalists sitting at home wondering what went wrong.
Boxing: Wales' Joe Calzaghe v England's Chris Eubank in 1997
Hot favourite Eubank was expected to beat the young pretender to his super middleweight crown, but instead ended up on the wrong side of the judges' decision after a scintillating bout in Manchester. Calzaghe knocked Eubank down in the opening moments to set the scene for a classic.
"I came out of the corner for round one smiling. I was moving around and sizing up the terrain," Eubanks said later, "When 'Boom!' Calzaghe hit me with a huge shot that literally came out of nowhere and knocked me down. A first-round knockdown had never happened to me in my entire career."
Calzaghe's astonishing opening assault was designed to win the bout early on - but while the tactic almost backfired, he battled through to win on points.
"I was knackered after three or four rounds when I hadn't stopped him," said Calzaghe. "I'd never gone 12 rounds in my life. I hope I never have to go through that sort of pain again. My body just wasn't used to it."
Football: Wales 4-1 England in 1980
Welsh heroes: James, Joey Jones, Thomas, Walsh, Nicholas, Giles, Flynn, Price, David Jones, Davies, Yorath
Wales's first home victory over England in 25 years came in Wrexham, at the ground where 11 years later Wrexham would stun Arsenal. Paul Mariner's opener put England ahead, but Mickey Thomas (who would score for Wrexham v Arsenal in 1991), Ian Walsh, Leighton James and Phil Thompson's own goal gave Wales their best ever win over their neighbours.
Snooker: Steve Davis 18-11 Terry Griffiths, World Championship final in 1988
Terry Griffiths's amazing performance nearly a decade after he first won the world title took the world of snooker by storm, but there was to be no fairytale ending for the Welshman. Steve Davis was clinical in the final, destroying the underdog and crowd favourite 18-11 to win the fifth of his six titles. Wales would have to wait another 12 years for a snooker world champion.
Football: England 0-1 Wales in 1977
The only ever Welsh victory against England at Wembley came in the Home Internationals in 1977. Wales, full of confidence after making the quarter-finals of the previous year's European Championships, won 1-0 thanks to a goal by Leighton James.
Athletics: Wales' Colin Jackson v England's Tony Jarrett
Two of Britain's truly world-class athletes had the misfortune to come through in the 110m hurdles at the exact same time in the late 1980s and early 1990s. At least it was unlucky for Jarrett, as Jackson beat him eight times in national championships and won two world championships while Jarrett ended up with a drawer full of silver medals.
Jarrett's lone gold at a major championships came at the 1998 Commonwealth Games - but even then Jackson managed to tarnish his achievement. The Welshman was absent after accepting a huge appearance fee to run at an event in Tokyo rather than go to the Games in Manchester.
Rugby: England 28-17 Wales in 2003
Pre-tournament favourites England had struggled to get through their group matches at the Rugby World Cup in Australia, and when the Welsh went 10-3 ahead at half-time a monumental victory seemed on the cards. But Mike Catt came on at half-time to settle England, who tore their opponents to shreds in the second half - a display which helped give them the momentum to go on and win the tournament.