Manchester City are this week's biggest losers with the Premier League champions counting the cost of a Champions League exit and a derby day defeat.
It has been a week to forget for Roberto Mancini's men, having been dumped out of Europe's premier club competition following defeat at Borussia Dortmund and then a loss against bitter rivals Manchester United in the dying moments of a highly-charged derby at the Etihad Stadium.
City's miserable last seven days are reflected in our rankings, where they are down 82 points from last week and fall a place to sixth. Their conquerors Dortmund leapfrog them into fifth, while fellow victors United stay in third despite dropping points overall after a defeat - albeit less damaging than those inflicted on City - to Cluj in the Champions League.
Elsewhere, Chelsea and Juventus are on the rise this week, with Shakhtar Donetsk dropping below both into 11th spot. Benfica and Valencia capitalise on Arsenal's Champions League slip-up against Olympiacos while AC Milan plunge three places to 19th after defeat to Zenit St Petersburg contributed to a net points loss of 44.
HOW IT WORKS
To determine our Power Rankings, we use the Euro Club Index, which scientifically analyses hundreds of thousands of matches from the top divisions in all European nations as well as Europa League and Champions League games.
The Index takes into account all matches played over an eight-year period but with recent results carrying more weight than older ones.
The performance of a league's teams in the Champions League and Europa League reflects the rise or fall of the sporting level in that league.
So, for example, if English teams perform well in Europe, all Premier League teams receive a small bonus in their ECI score. The ranking and its predictive power are thus made even more accurate.